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Preventing Mpox Resurgence
The Issue:
While the mpox outbreak has slowed, there is a continued risk of resurgence, especially without a focus on prevention efforts and vaccination with the JYNNEOS vaccine. Further, the 2022 outbreak showed that certain populations are affected by mpox more than others, including men who have sex with men (MSM) and LGBTQ+ (lesbian, gay, bisexual, transgender, queer and more) individuals.
Solution and Impact:
In September 2023, the CDC Foundation, in partnership with the Centers for Disease Control and Prevention (CDC), announced $5 million in support to 44 community-based organizations (CBOs) working to increase vaccine confidence, access and acceptance among those most affected by mpox. These organizations are trusted local resources and understand the historic and ongoing discrimination, inequities and stigma their community members face, especially around healthcare issues. CBOs communicate information about mpox prevention in clear, accurate and relevant ways, ensuring more people have the resources they need to make informed decisions about vaccination.
To help prevent a renewed mpox outbreak, CBOs have worked towards:
- Increasing availability of accurate information about the safety and effectiveness of the mpox vaccine delivered in innovative and culturally appropriate ways.
- Increasing mpox vaccine confidence, access and uptake in at-risk communities, including MSM, trans, HIV+ and LGBTQ+ individuals/communities as well as in Black and Hispanic communities
Strengthening Partnerships to Address Infection-Associated Chronic Conditions
Background
Infection Associated Chronic Conditions (IACCs) are chronic medical conditions that are initially triggered by an infection. While many different pathogens have been associated with the development of IACCs, different IACCs share several common features:
- IACCs tend to cause severe impacts to quality of life;
- IACCs typically impact a disproportionately high rate of female patients;
- IACCs are often characterized by neurological or immunological pathology; and
- IACCs comprise diffuse organ system interactions; and require multidisciplinary care.
Millions of Americans were living with IACCs prior to the COVID-19 pandemic, but the exact number is unknown. Large-scale epidemiological studies identifying the number or percentage of Americans with any IACC has not been undertaken to date. US population estimates of just a few IACCs published before or at the start of the COVID-19 pandemic suggest that these conditions were already widespread
About the Project
The global COVID-19 pandemic has created unprecedented awareness of the long-term health effects of IACCs. The number of people living with Long COVID-associated conditions or other infection-associated conditions—including myalgic encephalomyelitis/chronic fatigue syndrome, postural orthostatic tachycardia syndrome and other forms of dysautonomia, mast-cell activation syndrome, persistent Lyme disease/chronic Lyme disease and more—continue to increase.
Through the Infection Initiated Chronic Conditions Understanding and Engagement (ICUE) program, the CDC Foundation, in partnership with the Centers for Disease Control and Prevention (CDC), are bringing together patient advocacy groups and community-based organizations focused on raising awareness and helping people living with IACCs to identify common priorities and opportunities to collaborate, including exploring the development of an IACC Patient Advocacy Coalition (IACCPAC).
Summary Report
We’re pleased to announce that the first summary report, following our series of workshops on the needs and priorities of the infection-associated chronic conditions patient community, by the IACCPAC—a part of the IACCPAC Initiative, led by The Long Covid Alliance, Solve ME/CFS Initiative, COVID-19 Longhauler Advocacy Project, Dysautonomia International, and Patient-Led Research Collaborative, with support from the CDC Foundation through the ICUE program—is now available and can be accessed here.
Partners
- Dysautonomia International
- Commonality, Inc.
- Solve ME/CFS Initiative, Inc.
- Patient-Led Research Collaborative
- COVID-19 Longhauler Advocacy Project
This project is supported by the Centers for Disease Control and Prevention (CDC) of the U.S. Department of Health and Human Services (HHS) as part of a financial assistance award totaling $77,990 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement by, CDC/HHS, or the U.S. Government.
Rotavirus Vaccine Impact and Effectiveness Assessments
Characterization of Non-Rotavirus Viral Diarrheal Pathogens
Origin of Innate Immunity Suppression
Mechanisms of Norovirus Protective Immunity
Pagination
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